Pardridge, William: search on Z-Library

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1

DRUG AND GENE TARGETING TO THE BRAIN WITH MOLECULAR TROJAN HORSES

Pardridge, William M.

Journal:

Nature Reviews Drug Discovery

Year:

2002

Language:

english

File:

PDF, 1.01 MB

english, 2002

2

Brain drug delivery and blood–brain barrier transport

Pardridge, William M.

Journal:

Year:

1996

Language:

english

File:

PDF, 1.95 MB

english, 1996

3

Measurement of Amyloid Peptide Precursor of Alzheimer Disease in Human Blood by Double Antibody Immunoradiometric Assay

Pardridge, William M., Buciak, Jody L., Yang, Jing, Miller, Bruce L., Vinters, Harry V.

Journal:

Alzheimer Disease & Associated Disorders

Year:

1991

File:

PDF, 673 KB

1991

4

Transport of Albumin-bound Melatonin Through the Blood-Brain Barrier

William M. Pardridge, Lawrence J. Mietus

Journal:

Journal of Neurochemistry

Year:

1980

Language:

english

File:

PDF, 294 KB

english, 1980

5

Log(BB), PS products and in silico models of drug brain penetration

William M. Pardridge

Journal:

Drug Discovery Today

Year:

2004

Language:

english

File:

PDF, 31 KB

english, 2004

6

Translational science: what is it and why is it so important?

William M Pardridge

Journal:

Drug Discovery Today

Year:

2003

Language:

english

File:

PDF, 72 KB

english, 2003

7

Strategies for drug delivery through the blood-brain barrier

Pardridge, William M.

Journal:

Neurobiology of Aging

Year:

1989

Language:

english

File:

PDF, 235 KB

english, 1989

8

Molecular Trojan horses for blood–brain barrier drug delivery

William M Pardridge

Journal:

Current Opinion in Pharmacology

Year:

2006

Language:

english

File:

PDF, 229 KB

english, 2006

9

Amplification of gene expression using both 5′- and 3′-untranslated regions of GLUT1 glucose transporter mRNA

Ruben J. Boado, William M. Pardridge

Journal:

Molecular Brain Research

Year:

1999

Language:

english

File:

PDF, 236 KB

english, 1999

10

Chimeric peptides as a vehicle for peptide pharmaceutical delivery through the blood-brain barrier

William M. Pardridge, Arno K. Kumagai, Jody B. Eisenberg

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 514 KB

english, 1987

11

Delivery of peptides and proteins through the blood–brain barrier

Ulrich Bickel, Takayoshi Yoshikawa, William M. Pardridge

Journal:

Advanced Drug Delivery Reviews

Year:

2001

Language:

english

File:

PDF, 1.44 MB

english, 2001

12

Two-Day Starvation Does Not Alter the Kinetics of Blood-Brain Barrier Transport and Phosphorylation of Glucose in Rat Brain

Crane, Paul D., Pardridge, William M., Braun, Leon D., Oldendorf, William H.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

1985

Language:

english

File:

PDF, 384 KB

english, 1985

13

CSF, blood-brain barrier, and brain drug delivery

Pardridge, William M.

Journal:

Expert Opinion on Drug Delivery

Year:

2016

Language:

english

File:

PDF, 922 KB

english, 2016

14

Safety and clinical efficacy of AGT-181, a brain penetrating human insulin receptor antibody-iduronidase fusion protein, in a 26-week study with pediatric patients with mucopolysaccharidosis type I

Giugliani, Roberto, Giugliani, Luciana, Corte, Amauri Dalla, Poswar, Fabiano, Donis, Karina, Schmidt, Mathias, Hunt, Douglas, Boado, Ruben J., Pardridge, William M.

Journal:

Molecular Genetics and Metabolism

Year:

2018

Language:

english

File:

PDF, 52 KB

english, 2018

15

Decline in Exogenous Gene Expression in Primate Brain Following Intravenous Administration Is Due to Plasmid Degradation

Chun Chu, Yun Zhang, Ruben J. Boado, William M. Pardridge

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 216 KB

english, 2006

16

Restrictive Transport of a Lipid-Soluble Peptide (Cyclosporin) Through the Blood–Brain Barrier

William T. Cefalu, William M. Pardridge

Journal:

Journal of Neurochemistry

Year:

1985

Language:

english

File:

PDF, 314 KB

english, 1985

17

Carotid Artery Injection Technique: Bounds for Bolus Mixing by Plasma and by Brain

Pardridge, William M., Landaw, Elliot M., Miller, Leonard P., Braun, Leon D., Oldendorf, William H.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

1985

Language:

english

File:

PDF, 388 KB

english, 1985

18

Brain Capillary 46,000 Dalton Protein is Cytoplasmic Actin and is Localized to Endothelial Plasma Membrane

Pardridge, William M., Nowlin, Dawn M., Choi, Thomas B., Yang, Jing, Calaycayand, Jimmy, Shively, John E.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

1989

Language:

english

File:

PDF, 490 KB

english, 1989

19

Vascular Genomics of the Human Brain

Shusta, Eric V., Boado, Ruben J., Mathern, Gary W., Pardridge, William M.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2002

Language:

english

File:

PDF, 1.68 MB

english, 2002

20

Blood-Brain Barrier Transport of 125I-Labeled Basic Fibroblast Growth Factor

Yoshiharu Deguchi, Takafumi Naito, Takuro Yuge, Akihiko Furukawa, Shizuo Yamada, William M. Pardridge, Ryohei Kimura

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 428 KB

english, 2000

21

Crossing the blood–brain barrier: are we getting it right?

William M Pardridge

Journal:

Drug Discovery Today

Year:

2001

Language:

english

File:

PDF, 28 KB

english, 2001

22

Insulin therapy normalizes GLUT1 glucose transporter mRNA but not immunoreactive transporter protein in streptozocin-diabetic rats

Amy J. Lutz, William M. Pardridge

Journal:

Year:

1993

Language:

english

File:

PDF, 793 KB

english, 1993

23

Imaging gene expression in the brain with peptide nucleic acid (PNA) antisense radiopharmaceuticals and drug targeting technology

Ruben J. Boado, William M. Pardridge

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2003

Language:

english

File:

PDF, 676 KB

english, 2003

24

The Blood-Brain Barrier and Neurotherapeutics

William M. Pardridge

Journal:

Neurotherapeutics

Year:

2005

Language:

english

File:

PDF, 53 KB

english, 2005

25

Pharmacokinetics and Brain Uptake of an IgG-TNF Decoy Receptor Fusion Protein Following Intravenous, Intraperitoneal, and Subcutaneous Administration in Mice

Sumbria, Rachita K., Zhou, Qing-Hui, Hui, Eric Ka-Wai, Lu, Jeff Zhiqiang, Boado, Ruben J., Pardridge, William M.

Journal:

Molecular Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 2.02 MB

english, 2013

26

Platform technology for treatment of the brain in lysosomal disorders

Kelaita, Derek, Hui, Eric K.-W., Lu, Jeff Z., Lin, Huilan, Boado, Ruben J., Pardridge, William M.

Journal:

Molecular Genetics and Metabolism

Year:

2018

Language:

english

File:

PDF, 47 KB

english, 2018

27

Humanization of anti-human insulin receptor antibody for drug targeting across the human blood–brain barrier

Ruben J. Boado, Yufeng Zhang, Yun Zhang, William M. Pardridge

Journal:

Biotechnology and Bioengineering

Year:

2007

Language:

english

File:

PDF, 283 KB

english, 2007

28

Glucose deprivation and hypoxia increase the expression of the GLUT1 glucose transporter via a specific mRNA cis-acting regulatory element

Ruben J. Boado, William M. Pardridge

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 96 KB

english, 2002

29

Inorganic mercury: selective effects on blood-brain barrier transport systems

William M. Pardridge

Journal:

Journal of Neurochemistry

Year:

1976

Language:

english

File:

PDF, 264 KB

english, 1976

30

Blood–Brain Barrier Protein and Phosphorylation and Dephosphorylation

William M. Pardridge, Jing Yang, Jody Eisenberg

Journal:

Journal of Neurochemistry

Year:

1985

Language:

english

File:

PDF, 1.41 MB

english, 1985

31

Differential glycosylation of the GLUT1 glucose transporter in brain capillaries and choroid plexus

Arno K. Kumagai, Kenneth J. Dwyer, William M. Pardridge

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1994

Language:

english

File:

PDF, 833 KB

english, 1994

32

High molecular weight Alzheimer's disease amyloid peptide immunoreactivity in human serum and CSF is an immunoglobulin G

William M. Pardridge, Harry V. Vinters, Bruce L. Miller, Wallace W. Tourtellotte, Jody B. Eisenberg, Jing Yang

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 572 KB

english, 1987

33

Brain drug delivery and blood–Brain barrier transport

Pardridge, William M.

Journal:

Year:

1993

Language:

english

File:

PDF, 2.20 MB

english, 1993

34

Pharmacologic Effects in vivo in Brain by Vector-Mediated Peptide Drug Delivery

Ulrich Bickel, Takayoshi Yoshikawa, Elliot M. Landaw, Kym F. Faull and William M. Pardridge

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 886 KB

english, 1993

35

Augmented Transport and Metabolism of Sex Steroids in Lymphoid Neoplasia in the Rat*

CEFALU, WILLIAM T., PARDRIDGE, WILLIAM M.

Journal:

Year:

1987

Language:

english

File:

PDF, 1.76 MB

english, 1987

36

Blood-Brain Barrier Glucose Transporter is Asymmetrically Distributed on Brain Capillary Endothelial Lumenal and Ablumenal Membranes: An Electron Microscopic Immunogold Study

Catherine L. Farrell and William M. Pardridge

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.14 MB

english, 1991

37

PROTECTIVE EFFECTS OF A BRAIN-PENETRATING BIOLOGIC TNF-ALPHA INHIBITOR IN A MOUSE MODEL OF ALZHEIMER’S DISEASE

Chang, Rudy, Knox, Jillian, Chang, Jae, Woods, Jeffery, Derbedrossian, Aram, Vasilevko, Vitaly, Cribbs, David H., Boado, Ruben, Pardridge, William M., Sumbria, Rachita

Journal:

Alzheimer's & Dementia

Year:

2017

Language:

english

File:

PDF, 160 KB

english, 2017

38

Brain drug targeting (The future of brain drug development) || Blood–brain barrier genomics

Pardridge, William M.

Year:

2001

Language:

english

File:

PDF, 4.39 MB

english, 2001

39

Introduction to the Blood-Brain Barrier (Methodology, Biology and Pathology) || The carotid artery single injection technique

Pardridge, William M.

Year:

1998

File:

PDF, 1.11 MB

1998

40

Engineering and expression of a chimeric transferrin receptor monoclonal antibody for blood–brain barrier delivery in the mouse

Ruben J. Boado, Yun Zhang, Yuntao Wang, William M. Pardridge

Journal:

Biotechnology and Bioengineering

Year:

2009

Language:

english

File:

PDF, 286 KB

english, 2009

41

Brain Drug Development and Brain Drug Targeting

William M. Pardridge

Journal:

Pharmaceutical Research

Year:

2007

Language:

english

File:

PDF, 187 KB

english, 2007

42

Matters Arising

Albert Gjedde, William M. Pardridge, Paul D. Crane, William H. Oldendorf

Journal:

Journal of Neurochemistry

Year:

1982

Language:

english

File:

PDF, 289 KB

english, 1982

43

Capillary Depletion Method for Quantification of Blood–Brain Barrier Transport of Circulating Peptides and Plasma Proteins

Domingo Triguero, Jody Buciak, William M. Pardridge

Journal:

Journal of Neurochemistry

Year:

1990

Language:

english

File:

PDF, 717 KB

english, 1990

44

Amyloid Angiopathy of Alzheimer's Disease: Amino Acid Composition and Partial Sequence of a 4,200-Dalton Peptide Isolated from Cortical Microvessels

William M. Pardridge, Harry V. Vinters, Jing Yang, Jody Eisenberg, Thomas B. Choi, Wallace W. Tourtellotte, Verena Huebner, John E. Shively

Journal:

Journal of Neurochemistry

Year:

1987

Language:

english

File:

PDF, 1.69 MB

english, 1987

45

Drug delivery of antisense molecules to the brain for treatment of Alzheimer's disease and cerebral AIDS

Ruben J. Boado, Haruhisa Tsukamoto, William M. Pardridge

Journal:

Journal of Pharmaceutical Sciences

Year:

1998

Language:

english

File:

PDF, 211 KB

english, 1998

46

Antibodies to Blood-Brain Barrier Bind Selectively to Brain Capillary Endothelial Lateral Membranes and to a 46K Protein

Pardridge, William M., Yang, Jing, Eisenberg, Jody, Mietus, Lawrence J.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

1986

Language:

english

File:

PDF, 1.16 MB

english, 1986

47

Blood-Brain Barrier Carrier-Mediated Transport and Brain Metabolism of Amino Acids

William M. Pardridge

Journal:

Neurochemical Research

Year:

1998

Language:

english

File:

PDF, 2.52 MB

english, 1998

48

Transport of [125I]transferrin through the rat blood-brain barrier

Stilianos Skarlatos, Takayoshi Yoshikawa, William M. Pardridge

Journal:

Year:

1995

Language:

english

File:

PDF, 796 KB

english, 1995

49

Blood-brain barrier glucose transporter mRNA is increased in experimental diabetes mellitus

Thomas B. Choi, Ruben J. Boado, William M. Pardridge

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 840 KB

english, 1989

50

Drug Targeting to the Brain

William M. Pardridge

Journal:

Pharmaceutical Research

Year:

2007

Language:

english

File:

PDF, 731 KB

english, 2007

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